Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645703 | 0.85 | L3MBTL1 (0.42) | HTTNPSR1TDP1 | |
| SCHEMBL9645639 | 0.81 | L3MBTL1 (0.46) | HTTNPSR1TDP1 | |
| SCHEMBL9645833 | 0.80 | EGFR (0.43) | CPA3FOLH1 | |
| SCHEMBL9558884 | 0.80 | PLA2G2A (0.49) | CPA3 | |
| SCHEMBL9644879 | 0.77 | MMP2 (0.41) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL11068279 | 0.77 | HTT (0.53) | HTTNPSR1TDP1FFAR1PTGDR2 | |
| SCHEMBL4271572 | 0.74 | ALDH1A1 (0.59) | HTTNPSR1TDP1FFAR1PTGDR2 | |
| SCHEMBL4272628 | 0.73 | FFAR1 (0.53) | HTTNPSR1TDP1FFAR1PTGDR2 | |
| SCHEMBL4542541 | 0.72 | ALDH1A1 (0.51) | HTTNPSR1TDP1 | |
| SCHEMBL30354385 | 0.70 | PRNP (0.46) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508004-A1 | Phenylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5145869-A | Treatment of irritable bowel syndrome, dyskinesia, pancreatist; hormone inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |