Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645693 | 0.87 | SLC1A1 (0.43) | EGFRPPARGPPARAALDH1A1LMNA | |
| SCHEMBL9558884 | 0.80 | PLA2G2A (0.49) | CPA3 | |
| SCHEMBL9645139 | 0.80 | CPA3 (0.42) | CPA3FOLH1 | |
| SCHEMBL26717442 | 0.74 | ALDH1A1 (0.39) | EGFRPPARGPPARAALDH1A1LMNA | |
| SCHEMBL7235863 | 0.73 | CTSB (0.57) | ALDH1A1SMN1; SMN2PPARD | |
| SCHEMBL27218104 | 0.71 | PRNP (0.49) | ALDH1A1LMNAGFERSMN1; SMN2 | |
| SCHEMBL27218106 | 0.71 | PRNP (0.49) | ALDH1A1LMNAGFERSMN1; SMN2 | |
| SCHEMBL9558477 | 0.69 | PLA2G2A (0.45) | PPARGPPARAALDH1A1LMNA | |
| SCHEMBL9645703 | 0.69 | L3MBTL1 (0.42) | LMNA | |
| SCHEMBL9749609 | 0.68 | KDM4E (0.38) | CPA3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508004-A1 | Phenylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5145869-A | Treatment of irritable bowel syndrome, dyskinesia, pancreatist; hormone inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |