Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645639 | 0.93 | L3MBTL1 (0.46) | L3MBTL1SLC1A1POLBMAPTMEN1 | |
| SCHEMBL9644879 | 0.87 | MMP2 (0.41) | L3MBTL1MAPTMEN1KMT2ATSHR | |
| SCHEMBL9645139 | 0.85 | CPA3 (0.42) | HTTNPSR1TDP1 | |
| SCHEMBL9645693 | 0.84 | SLC1A1 (0.43) | SLC1A1POLBMAPTKMT2ATDP1 | |
| SCHEMBL9558477 | 0.82 | PLA2G2A (0.45) | SLC1A1MAPTTSHRNPSR1LMNA | |
| SCHEMBL9646488 | 0.82 | HPGD (0.40) | MEN1KMT2ARAB9ALMNAATM | |
| SCHEMBL9644811 | 0.81 | CCKAR (0.48) | L3MBTL1TSHRLMNACYP3A4CYP2C9 | |
| SCHEMBL9645604 | 0.77 | CCKBR (0.44) | TSHRLMNACYP3A4CYP2C9 | |
| SCHEMBL7075493 | 0.73 | ALDH1A1 (0.43) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL2722625 | 0.73 | TSHR (0.44) | TSHRHTTNPSR1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508004-A1 | Phenylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5145869-A | Treatment of irritable bowel syndrome, dyskinesia, pancreatist; hormone inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |