Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | DPEP1 | P16444 | 3/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439749 | 1.00 | LAP3 (0.42) | LAP3NAAABCHEDPEP1ENPP2 | |
| SCHEMBL10439822 | 0.81 | DPEP1 (0.50) | DPEP1 | |
| SCHEMBL9646445 | 0.81 | DPEP1 (0.50) | DPEP1 | |
| SCHEMBL9646250 | 0.76 | GRIK1 (0.47) | LAP3DPEP1 | |
| SCHEMBL9646228 | 0.76 | GRIK1 (0.47) | LAP3DPEP1 | |
| SCHEMBL9647029 | 0.73 | DPEP1 (0.44) | LAP3DPEP1 | |
| SCHEMBL9647019 | 0.73 | DPEP1 (0.44) | LAP3DPEP1 | |
| SCHEMBL10961437 | 0.72 | LAP3 (0.62) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL9647093 | 0.70 | ALDH1A1 (0.47) | LAP3DPEP1 | |
| SCHEMBL28712744 | 0.68 | CES2 (0.39) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | claimed |
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5145990-A | Dehydropeptidase, carbapenicillin potentiation | MERCK & CO., INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-4962097-A | IN COMBINATION WITH A CARBAPENEM OR PENEM ANTIBIOTIC | MERCK & CO., INC. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | disclosed |