SCHEMBL9646804

SCHEMBL9646804

Cc1ccc(Cl)cc1-c1[c]ccc(F)c1C(C)C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33
TGFBR1 P36897 1/20 0.33
CYP3A4 P08684 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30
RRM1 P23921 1/20 0.30
RRM2B Q7LG56 1/20 0.30
TSHR P16473 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9649284 0.77 CCNB2 (0.36)
SCHEMBL9649939 0.77
SCHEMBL9650453 0.77
SCHEMBL9649355 0.76 APP (0.35)
SCHEMBL9646840 0.75 TRPV3 (0.37)
SCHEMBL9648845 0.73
SCHEMBL9649043 0.71 PTGS2 (0.34)
SCHEMBL9649290 0.69 ACHE (0.31)
SCHEMBL28816121 0.69 IDO1 (0.38) IDO1CYP3A4LMNA
SCHEMBL9648679 0.68 L3MBTL1 (0.40) IDO1CYP3A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5120848-A Anticholesterol and antilipemic agents; hydroxy-3-methylglutaryl/3-/ coenzyme A reductase inhibitors GLAXO GROUP LIMITED (GB) 1992-06-09 US disclosed