Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9648823 | 0.85 | S1PR2 (0.39) | POLBKDM4EALDH1A1MDM2APEX1 | |
| SCHEMBL24027424 | 0.71 | KDM4E (0.35) | POLBKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL9648721 | 0.68 | LMNA (0.35) | POLBKDM4EALDH1A1SMN1; SMN2APEX1 | |
| SCHEMBL9649347 | 0.67 | LMNA (0.38) | POLBKDM4EALDH1A1SMN1; SMN2APEX1 | |
| SCHEMBL29185132 | 0.66 | EGLN2 (0.44) | — | |
| SCHEMBL9640678 | 0.65 | GLS (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL31703152 | 0.65 | ALDH1A1 (0.46) | POLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20579147 | 0.65 | KDM4E (0.37) | KDM4ENPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27951542 | 0.64 | S1PR2 (0.36) | POLBKDM4EALDH1A1APEX1 | |
| SCHEMBL9646921 | 0.64 | EIF2S1 (0.40) | POLBKDM4EALDH1A1SMN1; SMN2APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244728-B1 | USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0244728-A2 | Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |