SCHEMBL965016

SCHEMBL965016

O=S(=O)(Cl)CC1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH4 P08319 1/20 0.34
ADH7 P40394 1/20 0.34
CA1 P00915 3/20 0.33
CA12 O43570 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CHRM5 P08912 2/20 0.32
CYP1A2 P05177 1/20 0.32
ADRA2C P18825 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
EPHX1 P07099 2/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
ALOX5 P09917 1/20 0.31
CA2 P00918 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1149002 1.00 ADH1B (0.34) ADH1BADH1CADH1AADH4ADH7
SCHEMBL6958182 1.00 ADH1B (0.34) ADH1BADH1CADH1AADH4ADH7
SCHEMBL600653 0.97 ADH1B (0.31) ADH1BADH1CADH1AADH4ADH7
SCHEMBL746912 0.92
SCHEMBL623476 0.86
SCHEMBL4317449 0.82 CYP1A2 (0.41) ADH1BADH1CADH1AADH4ADH7
SCHEMBL23635861 0.77
SCHEMBL2930696 0.75 AOC2 (0.32)
SCHEMBL2151198 0.75 CYP1A2 (0.39) CYP1A2EPHX1HPGDCA2
SCHEMBL5278954 0.75 GABRA5 (0.39) CHRM1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115193419-B Magnetic microsphere, preparation method, application and diagnostic kit thereof 苏州纳微生命科技有限公司 2022-11-22 CN claimed
CN-115193419-A Magnetic microsphere, preparation method, application and diagnostic kit thereof 苏州纳微生命科技有限公司 2022-10-18 CN claimed
US-12545669-B2 Cycloalkyl and heterocycloalkyl benzisoxazole sulfonamide derivatives PFIZER INC. (US) 2026-02-10 US disclosed
US-20250282762-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF NOVARTIS AG (CH) 2025-09-11 US disclosed
US-12252482-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2025-03-18 US disclosed
US-20250051343-A1 INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES Isosterix, Inc. 2025-02-13 US disclosed
EP-4499609-A1 INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES Isosterix, Inc. (US) 2025-02-05 EP disclosed
CN-119301096-A Inhibitors of MYST family lysine acetyltransferase 伊索斯泰里克斯公司 2025-01-10 CN disclosed
US-12187732-B2 Inhibitors of the myst family of lysine acetyl transferases Isosterix, Inc. (US) 2025-01-07 US disclosed
US-20250002479-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2025-01-02 US disclosed
US-12172984-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2024-12-24 US disclosed
US-5668289-A Pyridinone thrombin inhibitors MERCK & CO., INC. (US) 1997-09-16 US disclosed
US-5658926-A ANTICOAGULANTS, ANTIHISTAMINES, ANTIARRHYTHMIC, CARTIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-08-19 US disclosed
US-5658939-A PREVENTION THROMBOSIS IN MAMMALS CORVAS INTERNATIONAL INC. (US) 1997-08-19 US disclosed
US-5646165-A ANTITHROMBOTIC AGENTS CORVAS INTERNATIONAL, INC. (US) 1997-07-08 US disclosed
EP-0765340-A1 METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS CORVAS INTERNATIONAL, INC. (US) 1997-04-02 EP disclosed
WO-1997001338-A1 PYRIDINONE-THROMBIN INHIBITORS MERCK & CO., INC. (US) 1997-01-16 WO disclosed
US-5506239-A Carbostyril derivative and platelets aggregation inhibitory agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-04-09 US disclosed
WO-1995028420-A1 METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS CORVAS INTERNATIONAL, INC. (US) 1995-10-26 WO disclosed
EP-0569592-A1 CARBOSTYRIL DERIVATIVE AND PLATELET AGGLUTINATION INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051343-A1 INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES KAT6A, KAT6B, KAT2A ADH1B 1502/4885ADH1C 2251/4885ADH1A 1824/4885
US-12172984-B2 Pyrazolopyridine derivatives and uses thereof HBZ, ZFX, WIZ ADH1B 1657/4885ADH1C 1774/4885ADH1A 3016/4885
US-12252482-B2 Pyrazolopyridine derivatives and uses thereof HBZ, ZFX, WIZ ADH1B 1657/4885ADH1C 1774/4885ADH1A 3016/4885
US-20250282762-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF HBZ, ZFX, WIZ ADH1B 1657/4885ADH1C 1774/4885ADH1A 3016/4885
US-12187732-B2 Inhibitors of the myst family of lysine acetyl transferases KAT6A, KAT6B, KAT2A ADH1B 1502/4885ADH1C 2251/4885ADH1A 1824/4885
US-12545669-B2 Cycloalkyl and heterocycloalkyl benzisoxazole sulfonamide derivatives NHERF1, CBX8, BCL9 ADH1B 3783/4885ADH1C 2111/4885ADH1A 2187/4885
US-20250002479-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF HBZ, ZFX, WIZ ADH1B 1657/4885ADH1C 1774/4885ADH1A 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.