Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094550 | 0.92 | DRD2 (0.35) | DRD2 | |
| SCHEMBL9093955 | 0.88 | HRH3 (0.38) | DRD2HRH3FFAR1HTR1AL3MBTL1 | |
| SCHEMBL9094482 | 0.88 | HRH3 (0.38) | DRD2HRH3FFAR1HTR1AL3MBTL1 | |
| SCHEMBL9093897 | 0.88 | HRH3 (0.38) | DRD2HRH3FFAR1HTR1AL3MBTL1 | |
| SCHEMBL9094537 | 0.84 | CHRNB4 (0.42) | CHRNB4CHRNA3DRD2HRH3DRD4 | |
| SCHEMBL9092839 | 0.83 | HTR1A (0.47) | TP53HTR1AL3MBTL1 | |
| SCHEMBL9093992 | 0.83 | EPHX2 (0.34) | HRH3DRD4HTR1A | |
| SCHEMBL9095192 | 0.83 | SLC6A5 (0.36) | HRH3HTR1A | |
| SCHEMBL9093960 | 0.78 | LMNA (0.32) | DRD2 | |
| SCHEMBL9094981 | 0.77 | CCR5 (0.37) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505465-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION. | NOVO NORDISK AS (DK) | 1992-09-30 | — | — | EP | disclosed |
| US-5102894-A | Antihyporic, antiischemic, antiepileptic agents | NOVO NORDISK A/S (DK) | 1992-04-07 | — | — | US | disclosed |
| WO-1991009032-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION | NOVO NORDISK A/S (DK) | 1991-06-27 | — | — | WO | disclosed |