Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.44 |
| ▸ | HRH2 | P25021 | 9/20 | 0.44 |
| ▸ | HRH1 | P35367 | 9/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655435 | 0.89 | DRD2 (0.49) | HRH3 | |
| SCHEMBL9653371 | 0.83 | KDM4E (0.45) | HRH3HRH1SIGMAR1 | |
| SCHEMBL9654170 | 0.82 | DRD2 (0.50) | HRH3 | |
| SCHEMBL5083239 | 0.74 | DRD2 (0.56) | HRH3SIGMAR1 | |
| SCHEMBL5076789 | 0.72 | ADRA1D (0.50) | HRH3SIGMAR1MEN1 | |
| SCHEMBL11523258 | 0.72 | HRH3 (0.39) | HRH3HRH2HRH1 | |
| SCHEMBL11523252 | 0.72 | HRH3 (0.39) | HRH3HRH2HRH1 | |
| SCHEMBL9912154 | 0.70 | DRD2 (0.44) | HRH3 | |
| SCHEMBL9094149 | 0.70 | HRH3 (0.44) | HRH3HRH2HRH1SIGMAR1MEN1 | |
| SCHEMBL9094096 | 0.70 | HRH3 (0.44) | HRH3HRH2HRH1SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505465-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION. | NOVO NORDISK AS (DK) | 1992-09-30 | — | — | EP | claimed |
| WO-1991009032-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION | NOVO NORDISK A/S (DK) | 1991-06-27 | — | — | WO | claimed |