Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5076789 | 0.89 | ADRA1D (0.50) | DRD2HRH3SIGMAR1 | |
| SCHEMBL9655435 | 0.85 | DRD2 (0.49) | DRD2OPRM1HRH3 | |
| SCHEMBL9654170 | 0.77 | DRD2 (0.50) | DRD2HRH3 | |
| SCHEMBL9531948 | 0.75 | HRH3 (0.59) | HRH3 | |
| SCHEMBL9652034 | 0.75 | DRD2 (0.47) | DRD2HRH3 | |
| SCHEMBL9655196 | 0.74 | HRH3 (0.44) | HRH3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9530694 | 0.72 | LTA4H (0.61) | HRH3 | |
| SCHEMBL8104014 | 0.72 | DRD2 (0.68) | DRD2SLC18A3SIGMAR1CARM1PRMT6 | |
| Anisole SCHEMBL28123646 | 0.72 | CA4 (0.47) | DRD2 | |
| SCHEMBL8091036 | 0.71 | SIGMAR1 (0.76) | DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133884-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-11-06 | — | — | WO | disclosed |