Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655435 | 0.90 | DRD2 (0.49) | DRD2HRH3TLR9TLR7SLC6A4 | |
| SCHEMBL9653371 | 0.85 | KDM4E (0.45) | DRD2HRH3SLC6A4 | |
| SCHEMBL9652034 | 0.84 | DRD2 (0.47) | DRD2HRH3TP53GAACHRNB4 | |
| SCHEMBL9655196 | 0.82 | HRH3 (0.44) | HRH3 | |
| SCHEMBL5083239 | 0.77 | DRD2 (0.56) | DRD2HRH3 | |
| SCHEMBL9654191 | 0.77 | CCR2 (0.42) | DRD2SLC6A4 | |
| SCHEMBL9654252 | 0.71 | CHRNB4 (0.41) | DRD2HRH3TP53GAACHRNB4 | |
| SCHEMBL9652004 | 0.70 | DRD2 (0.43) | DRD2GAA | |
| SCHEMBL9094537 | 0.70 | CHRNB4 (0.42) | DRD2HRH3CHRNB4CHRNA3 | |
| SCHEMBL5076789 | 0.69 | ADRA1D (0.50) | DRD2HRH3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505465-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION. | NOVO NORDISK AS (DK) | 1992-09-30 | — | — | EP | disclosed |
| WO-1991009032-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION | NOVO NORDISK A/S (DK) | 1991-06-27 | — | — | WO | disclosed |