Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | CCR3 | P51677 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655435 | 0.86 | DRD2 (0.49) | SLC6A4HRH3CCR2DRD2CCR5 | |
| SCHEMBL9654170 | 0.85 | DRD2 (0.50) | SLC6A4HRH3DRD2 | |
| SCHEMBL9655196 | 0.83 | HRH3 (0.44) | HRH1HRH3SIGMAR1 | |
| SCHEMBL9654191 | 0.77 | CCR2 (0.42) | SLC6A4CCR2DRD2CCR5 | |
| SCHEMBL5083239 | 0.71 | DRD2 (0.56) | HRH3DRD2SIGMAR1 | |
| SCHEMBL9093940 | 0.70 | KDM4E (0.41) | KDM4EHRH1CCR3SLC6A4HRH3 | |
| SCHEMBL5076789 | 0.69 | ADRA1D (0.50) | KDM4EHRH3ALDH1A1DRD2ADRA1A | |
| SCHEMBL9652034 | 0.69 | DRD2 (0.47) | KDM4ESLC6A4HRH3ALDH1A1DRD2 | |
| SCHEMBL9912154 | 0.67 | DRD2 (0.44) | SLC6A4HRH3ALDH1A1DRD2SMN1; SMN2 | |
| SCHEMBL9652004 | 0.66 | DRD2 (0.43) | KDM4EALDH1A1DRD2POLBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505465-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION. | NOVO NORDISK AS (DK) | 1992-09-30 | — | — | EP | disclosed |
| WO-1991009032-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION | NOVO NORDISK A/S (DK) | 1991-06-27 | — | — | WO | disclosed |