Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652004 | 0.78 | DRD2 (0.43) | MEN1KMT2ADRD2 | |
| SCHEMBL9912154 | 0.76 | DRD2 (0.44) | SLC18A3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9654191 | 0.75 | CCR2 (0.42) | SLC18A3CCR2PRCPCCR5DRD2 | |
| SCHEMBL9910975 | 0.71 | QDPR (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9811479 | 0.69 | SIGMAR1 (0.50) | SLC18A3CCR2PRCPKMT2ADRD2 | |
| SCHEMBL28713027 | 0.66 | ESR2 (0.55) | SLC18A3CHRM1 | |
| SCHEMBL6184621 | 0.66 | CHRM1 (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9093960 | 0.65 | LMNA (0.32) | SLC18A3CCR5DRD2LMNA | |
| SCHEMBL9811419 | 0.65 | CCR2 (0.40) | SLC18A3CCR2PRCPCCR5DRD2 | |
| SCHEMBL3089324 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502024-A1 | 4-HETEROARYL PIPERIDINE INTERMEDIATES AND THEIR PREPARATION. | NOVO NORDISK AS (DK) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007398-A1 | 4-HETEROARYL PIPERIDINE INTERMEDIATES AND THEIR PREPARATION | NOVO NORDISK A/S (DK) | 1991-05-30 | — | — | WO | claimed |