Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655435 | 0.80 | DRD2 (0.49) | CCR2CCR5DRD2SLC6A4 | |
| SCHEMBL9654472 | 0.79 | CCR5 (0.39) | CCR5DRD2SLC18A3DRD3SLC6A4 | |
| SCHEMBL9655196 | 0.78 | HRH3 (0.44) | — | |
| SCHEMBL9653371 | 0.77 | KDM4E (0.45) | CCR2CCR5DRD2SLC6A4 | |
| SCHEMBL9912154 | 0.76 | DRD2 (0.44) | DRD2SLC18A3DRD3SLC6A4 | |
| SCHEMBL9655545 | 0.75 | SLC18A3 (0.41) | CCR2CCR5DRD2SLC18A3PRCP | |
| SCHEMBL9910975 | 0.71 | QDPR (0.47) | DRD2 | |
| Hydrochloric Acid SCHEMBL9811479 | 0.71 | SIGMAR1 (0.50) | CCR2DRD2SLC18A3PRCP | |
| SCHEMBL9342501 | 0.68 | ALDH1A1 (0.45) | CARM1PRMT6 | |
| SCHEMBL9811419 | 0.68 | CCR2 (0.40) | CCR2CCR5DRD2SLC18A3PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502024-A1 | 4-HETEROARYL PIPERIDINE INTERMEDIATES AND THEIR PREPARATION. | NOVO NORDISK AS (DK) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007398-A1 | 4-HETEROARYL PIPERIDINE INTERMEDIATES AND THEIR PREPARATION | NOVO NORDISK A/S (DK) | 1991-05-30 | — | — | WO | claimed |
| EP-0505465-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION. | NOVO NORDISK AS (DK) | 1992-09-30 | — | — | EP | disclosed |
| EP-0502024-A1 | 4-HETEROARYL PIPERIDINE INTERMEDIATES AND THEIR PREPARATION. | NOVO NORDISK AS (DK) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991009032-A1 | PIPERIDINE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION | NOVO NORDISK A/S (DK) | 1991-06-27 | — | — | WO | disclosed |
| WO-1991007398-A1 | 4-HETEROARYL PIPERIDINE INTERMEDIATES AND THEIR PREPARATION | NOVO NORDISK A/S (DK) | 1991-05-30 | — | — | WO | disclosed |