Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660909 | 1.00 | KIF11 (0.39) | KIF11PTGS2HRH4PTGS1CACNA1B | |
| SCHEMBL9660700 | 0.88 | ALDH1A1 (0.35) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL9660705 | 0.88 | ALDH1A1 (0.35) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL9658808 | 0.85 | ALDH1A1 (0.37) | MAPTSMN1; SMN2 | |
| SCHEMBL9658803 | 0.85 | ALDH1A1 (0.37) | MAPTSMN1; SMN2 | |
| SCHEMBL9660368 | 0.80 | NPC1 (0.37) | KDM4EMEN1LMNAMAPTHTT | |
| SCHEMBL9660795 | 0.74 | KMT2A (0.36) | MEN1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9660787 | 0.74 | KMT2A (0.36) | MEN1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9690129 | 0.74 | CA12 (0.43) | KDM4EMEN1LMNAMAPTHTT | |
| SCHEMBL9690121 | 0.74 | CA12 (0.43) | KDM4EMEN1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |