Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15518976 | 0.88 | SLC1A3 (0.42) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL3701482 | 0.82 | TSHR (0.48) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL360511 | 0.82 | TSHR (0.48) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL10784028 | 0.81 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL15003 | 0.81 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL1571975 | 0.81 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| Lithium SCHEMBL9504699 | 0.79 | TSHR (0.50) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL21518155 | 0.79 | TSHR (0.50) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL9504704 | 0.79 | TSHR (0.50) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL94896 | 0.78 | CA1 (0.46) | TSHRALDH1A1IDO1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421533-B1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP (CA) | 2018-10-17 | — | — | EP | claimed |
| CN-107252429-A | New antiinflammatory | 雷斯韦洛吉克斯公司 | 2017-10-17 | — | — | CN | claimed |
| WO-2013186612-A1 | THE USE OF SUBSTITUTED 2-PHENYL-3H-QUINAZOLIN-4-ONES AND ANALOGS FOR INHIBITING BET (BROMODOMAIN AND EXTRA TERMINAL DOMAIN) PROTEINS | RVX THERAPEUTICS INC. (CA) | 2013-12-19 | — | — | WO | claimed |
| WO-2013175281-A1 | USE OF SUBSTITUTED 2-PHENYL-3H-QUINAZOLIN-4-ONES AND ANALOGS FOR INHIBITING BROMODOMAIN AND EXTRA TERMINAL DOMAIN (BET) PROTEINS | RVX THERAPEUTICS INC. (CA) | 2013-11-28 | — | — | WO | claimed |
| US-20130281398-A1 | TREATMENT OF DISEASES BY EPIGENETIC REGULATION | RVX THERAPEUTICS INC. (CA) | 2013-10-24 | — | — | US | claimed |
| US-20130281399-A1 | TREATMENT OF DISEASES BY EPIGENETIC REGULATION | RVX THERAPEUTICS INC. (CA) | 2013-10-24 | — | — | US | claimed |
| US-20120059002-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | HEPALINK (HONG KONG) LIMITED (HK) | 2012-03-08 | — | — | US | claimed |
| EP-2421533-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2012-02-29 | — | — | EP | claimed |
| EP-2408454-A2 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2012-01-25 | — | — | EP | claimed |
| WO-2010123975-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2010-10-28 | — | — | WO | claimed |
| EP-0415212-A1 | Aryloxynaphthalene derivatives | BAYER AG (DE) | 1991-03-06 | — | — | EP | claimed |
| EP-0269806-B1 | PHENYLPYRAZOLE CARBONIC ACID DERIVATIVES, THEIR PREPARATION AND USE AS PLANT GROWTH REGULATORS AND ANTIDOTES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | claimed |
| US-4891057-A | Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | claimed |
| EP-0269806-A1 | Phenylpyrazole carbonic acid derivatives, their preparation and use as plant growth regulators and antidotes | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-08 | — | — | EP | claimed |
| US-4747868-A | Growth-regulating, fungicidal, and herbicidal cyclohexylimidazole and cyclohexenylimidazole derivatives, compositions, and methods of use therefor | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | claimed |
| EP-0243918-A2 | 1-Phenyl-imidazole compounds, process for their preparation and their use as growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-04 | — | — | EP | claimed |
| EP-0219798-A1 | 1,2,5-Substituted imidazole compounds, method for their preparation and their use as growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-29 | — | — | EP | claimed |
| EP-0199206-A2 | Cyclohexyl- and cyclohexenylimidazole compounds, process for their preparation and their use as plant-protective agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-29 | — | — | EP | claimed |
| EP-0185961-A2 | 1-Phenyl-imidazole-5-carboxylic acid derivatives, process for their preparation and their use as growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-02 | — | — | EP | claimed |
| US-4011320-A | PESTICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1977-03-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281399-A1 | TREATMENT OF DISEASES BY EPIGENETIC REGULATION | PHKB, BAZ2A, EP300 | TSHR 3086/4885SLC1A3 3725/4885SLC1A2 3748/4885 |
| US-20120059002-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | VCAM1, ICAM1, IL6 | TSHR 4123/4885SLC1A3 3553/4885SLC1A2 3811/4885 |
| US-20130281398-A1 | TREATMENT OF DISEASES BY EPIGENETIC REGULATION | PHKB, BAZ2A, EP300 | TSHR 3086/4885SLC1A3 3725/4885SLC1A2 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.