Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 7/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670239 | 1.00 | GPR52 (0.37) | GPR52EPHX2FAAH | |
| SCHEMBL9671433 | 0.88 | FAAH (0.44) | FAAH | |
| SCHEMBL9670251 | 0.85 | FAAH (0.38) | FAAH | |
| SCHEMBL9670072 | 0.83 | GPR52 (0.37) | GPR52EPHX2 | |
| SCHEMBL9670067 | 0.83 | GPR52 (0.37) | GPR52EPHX2 | |
| SCHEMBL9671129 | 0.74 | CA2 (0.40) | — | |
| SCHEMBL9671527 | 0.74 | CA2 (0.40) | — | |
| SCHEMBL9734634 | 0.72 | LTB4R (0.44) | — | |
| SCHEMBL9670027 | 0.71 | ADRB2 (0.36) | — | |
| SCHEMBL9670650 | 0.70 | FAAH (0.40) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295056-B1 | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |