Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671527 | 0.82 | CA2 (0.40) | LTB4RFFAR1PTGER2ALDH1A1 | |
| SCHEMBL9670027 | 0.79 | ADRB2 (0.36) | LTB4RALDH1A1 | |
| SCHEMBL9671433 | 0.78 | FAAH (0.44) | TRPA1 | |
| Cyclohexane SCHEMBL10651191 | 0.77 | CA2 (0.36) | LTB4RPTGER2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL9670240 | 0.72 | GPR52 (0.37) | — | |
| SCHEMBL6907990 | 0.70 | TBXAS1 (0.58) | LTB4RFFAR4FFAR1TBXAS1TBXA2R | |
| SCHEMBL9308449 | 0.70 | TBXAS1 (0.58) | LTB4RFFAR4FFAR1TBXAS1TBXA2R | |
| SCHEMBL6907995 | 0.70 | TBXAS1 (0.58) | LTB4RFFAR4FFAR1TBXAS1TBXA2R | |
| SCHEMBL8742992 | 0.69 | TBXA2R (0.58) | LTB4RFFAR4FFAR1PTGER2PTGER4 | |
| SCHEMBL8743003 | 0.69 | TBXA2R (0.58) | LTB4RFFAR4FFAR1PTGER2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |