Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | NAMPT | P43490 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437426 | 0.86 | MMP2 (0.58) | RAB9AMEN1KMT2ANPC1LMNA | |
| SCHEMBL9670630 | 0.85 | ROCK2 (0.55) | RAB9AADRB2ADRB1ADRB3ROCK2 | |
| SCHEMBL2181161 | 0.84 | GRM5 (0.52) | IDO1ADRB2ADRB1ADRB3ROCK2 | |
| SCHEMBL29815107 | 0.84 | ROCK2 (0.50) | RAB9AADRB2ADRB1ADRB3ROCK2 | |
| SCHEMBL6016970 | 0.83 | ALDH1A1 (0.57) | RAB9AADRB2ADRB1ADRB3ROCK2 | |
| SCHEMBL9670317 | 0.80 | ROCK2 (0.49) | RAB9AADRB2ADRB1ADRB3ROCK2 | |
| SCHEMBL14340101 | 0.79 | KCNQ3 (0.57) | RAB9AADRB2ADRB1ADRB3ROCK2 | |
| SCHEMBL9816236 | 0.79 | FAAH (0.61) | RAB9AADRB2ADRB1ADRB3ROCK2 | |
| SCHEMBL14516675 | 0.78 | FAAH (0.50) | RAB9AADRB2ADRB1ADRB3ROCK2 | |
| SCHEMBL28372986 | 0.78 | RAB9A (0.71) | RAB9AMEN1KMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254322-B1 | BENZIMIDAZOLE DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-4886803-A | CARDIOTONIC AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0254322-A1 | Benzimidazole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-01-27 | — | — | EP | disclosed |