Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 7/20 | 0.54 |
| ▸ | HTR1A | P08908 | 7/20 | 0.54 |
| ▸ | HTR1B | P28222 | 6/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HTR5A | P47898 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314594 | 0.84 | HTR1D (0.53) | HTR1DHTR1AHTR1BDRD3DRD2 | |
| SCHEMBL10972396 | 0.83 | HTR1D (0.65) | HTR1DHTR1AHTR1BDRD3DRD2 | |
| SCHEMBL9670304 | 0.80 | DRD3 (0.62) | HTR1DHTR1AHTR1BDRD3DRD2 | |
| SCHEMBL9670081 | 0.77 | HTR1D (0.52) | HTR1DHTR1AHTR1BDRD3DRD2 | |
| SCHEMBL9669337 | 0.72 | HTR1D (0.60) | HTR1DHTR1AHTR1BDRD3DRD2 | |
| SCHEMBL8315482 | 0.70 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL10978045 | 0.69 | HTR6 (0.60) | HTR1DHTR1AHTR1BDRD3DRD2 | |
| SCHEMBL8886975 | 0.69 | ADRA1A (0.36) | HTR1DHTR1BDRD3DRD2ADRA1A | |
| SCHEMBL11042681 | 0.68 | DRD2 (0.62) | HTR1DHTR1AHTR1BDRD3DRD2 | |
| SCHEMBL6542199 | 0.67 | HTR1A (0.72) | HTR1DHTR1AHTR1BDRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510068-A1 | NEW CENTRALLY ACTING 6,7,8,9-TETRAHYDRO-3H-BENZ(e)INDOLE HETEROCYCLICS | PHARMACIA & UPJOHN COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |