Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616611 | 0.78 | PDCD4 (0.43) | — | |
| SCHEMBL8617164 | 0.78 | PDCD4 (0.43) | — | |
| SCHEMBL9671393 | 0.78 | NAAA (0.42) | — | |
| SCHEMBL9670290 | 0.75 | MCL1 (0.35) | MCL1MTNR1AKMT2AL3MBTL1KDM4E | |
| SCHEMBL9670188 | 0.69 | PDCD4 (0.41) | — | |
| SCHEMBL28789111 | 0.68 | LTB4R (0.52) | MCL1MTNR1AKMT2ASIGMAR1KDM4E | |
| SCHEMBL11552726 | 0.67 | MTNR1A (0.45) | MCL1MTNR1AKMT2AL3MBTL1SIGMAR1 | |
| SCHEMBL11256402 | 0.67 | MTNR1A (0.42) | MCL1MTNR1AKMT2AL3MBTL1SIGMAR1 | |
| SCHEMBL11709614 | 0.67 | SIGMAR1 (0.51) | KMT2ASIGMAR1 | |
| SCHEMBL6863376 | 0.67 | SIGMAR1 (0.51) | KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295056-B1 | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |