Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 5/20 | 0.33 |
| ▸ | FLT4 | P35916 | 5/20 | 0.33 |
| ▸ | KDR | P35968 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677074 | 0.88 | STS (0.40) | L3MBTL1SMN1; SMN2POLBLMNA | |
| SCHEMBL9678305 | 0.80 | FLT1 (0.43) | FLT1FLT4KDRCNR1POLB | |
| SCHEMBL9678285 | 0.79 | MEN1 (0.34) | FLT1FLT4KDRHSD11B1CNR1 | |
| SCHEMBL9676571 | 0.78 | POLB (0.38) | HSD11B1POLBLMNA | |
| SCHEMBL9676037 | 0.70 | CA1 (0.44) | POLBMAPT | |
| SCHEMBL9676160 | 0.68 | ALPL (0.39) | HSD11B1 | |
| SCHEMBL9679153 | 0.67 | HTR6 (0.42) | FLT1FLT4KDRHSD11B1CNR1 | |
| SCHEMBL9677148 | 0.67 | HTR6 (0.42) | L3MBTL1SMN1; SMN2CNR1LMNA | |
| SCHEMBL9678562 | 0.67 | RORC (0.36) | HSD11B1CNR1POLBMAPT | |
| SCHEMBL14534750 | 0.65 | ALDH1A1 (0.42) | FLT1FLT4KDRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |