Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678856 | 0.87 | P2RY12 (0.42) | HTR6RIPK1GAACNR1 | |
| SCHEMBL9678657 | 0.85 | CACNA1H (0.39) | RIPK1CACNA1HLMNATERTCACNA1C | |
| SCHEMBL9679224 | 0.85 | RIPK1 (0.54) | STSHTR6RIPK1CACNA1HLMNA | |
| SCHEMBL9678772 | 0.85 | STS (0.43) | STSHTR6ATMRIPK1CACNA1H | |
| SCHEMBL9677235 | 0.79 | HTR6 (0.44) | STSHTR6ATMRIPK1LMNA | |
| SCHEMBL9678253 | 0.78 | HTR6 (0.47) | STSHTR6ATMLMNAGAA | |
| SCHEMBL9678365 | 0.74 | RIPK1 (0.56) | HTR6RIPK1CACNA1HLMNAGAA | |
| SCHEMBL9677074 | 0.73 | STS (0.40) | STSHTR6ATMLMNAGAA | |
| SCHEMBL9676937 | 0.72 | RIPK1 (0.53) | RIPK1CACNA1HLMNAGAATERT | |
| SCHEMBL9678539 | 0.71 | HTR6 (0.49) | STSHTR6ATMRIPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |