Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 5/20 | 0.48 |
| ▸ | SOAT2 | O75908 | 3/20 | 0.48 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NMBR | P28336 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680743 | 0.95 | SOAT1 (0.51) | SOAT1SOAT2ACAT1KMT2AMEN1 | |
| SCHEMBL9679354 | 0.90 | SOAT1 (0.47) | SOAT1SOAT2ACAT1KMT2AMEN1 | |
| SCHEMBL9679702 | 0.87 | SOAT1 (0.49) | SOAT1SOAT2ACAT1KMT2AMEN1 | |
| SCHEMBL9679689 | 0.85 | RECQL (0.45) | SOAT1SOAT2ACAT1KMT2AMEN1 | |
| SCHEMBL9765050 | 0.82 | SOAT1 (0.51) | SOAT1SOAT2ACAT1KMT2AMEN1 | |
| SCHEMBL9765049 | 0.79 | SOAT2 (0.48) | SOAT1SOAT2ACAT1 | |
| SCHEMBL9679390 | 0.79 | ALDH1A1 (0.58) | SOAT1SOAT2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9678897 | 0.78 | SOAT1 (0.57) | SOAT1SOAT2ACAT1KMT2AMEN1 | |
| SCHEMBL3409396 | 0.77 | KMT2A (0.43) | SOAT1SOAT2ACAT1KMT2AMEN1 | |
| SCHEMBL9680651 | 0.76 | THRB (0.48) | SOAT1SOAT2ACAT1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |