Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.45 |
| ▸ | MAOB | P27338 | 11/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725001 | 0.85 | MAOA (0.59) | MAOAMAOBPTGS2PPOXGSK3B | |
| SCHEMBL23945629 | 0.76 | MAOA (0.50) | MAOAMAOBPTGS2PPOX | |
| SCHEMBL11669965 | 0.76 | ROS1 (0.49) | MAOAMAOBALDH1A1GAAMAPT | |
| SCHEMBL12219880 | 0.73 | HPGD (0.47) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL8726573 | 0.72 | PPOX (0.70) | MAOAMAOBKDM4EMAPTPPOX | |
| SCHEMBL11669501 | 0.71 | ALDH1A1 (0.53) | MAOAMAOBALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL2098566 | 0.70 | TDP2 (0.47) | MAOAMAOBPPOX | |
| SCHEMBL11685503 | 0.70 | PTGS2 (0.39) | PTGS2PPOXWEE1 | |
| SCHEMBL29036115 | 0.70 | MCL1 (0.46) | MAOAMAOBKDM4EALDH1A1GAA | |
| SCHEMBL84289 | 0.69 | PTGS2 (0.47) | MAOAMAOBPTGS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473491-B1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARM CO LTD (JP) | 2013-07-17 | — | — | EP | disclosed |
| US-5106814-A | Containing aromatic isocyanate, imino compound, trialkoxy benzoate; image stability, responsiveness | MITSUBISHI PAPER MILLS LIMITED (JP) | 1992-04-21 | — | — | US | disclosed |
| US-4065462-A | ORGANIC PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4016157-A | COLORING PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |