Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682129 | 0.88 | ALDH1A1 (0.36) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL9680897 | 0.86 | ALDH1A1 (0.43) | RAB9AMAPTRECQLALDH1A1KDM4E | |
| SCHEMBL9680903 | 0.85 | SMN1; SMN2 (0.41) | RAB9AMAPTALDH1A1KDM4EGLA | |
| SCHEMBL9682106 | 0.85 | ALDH1A1 (0.42) | RAB9AMAPTALDH1A1KDM4EGLA | |
| SCHEMBL9681489 | 0.82 | ALDH1A1 (0.41) | RAB9AMAPTALDH1A1KDM4EGLA | |
| SCHEMBL9682156 | 0.82 | ALDH1A1 (0.38) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL9680406 | 0.82 | POLB (0.45) | RAB9AMAPTALDH1A1KDM4EGLA | |
| SCHEMBL9681433 | 0.80 | CFTR (0.42) | MAPTALDH1A1KDM4EGLAGAA | |
| SCHEMBL9682059 | 0.79 | MAPT (0.45) | MAPTRECQLALDH1A1KDM4EGLA | |
| SCHEMBL9682845 | 0.73 | PDGFRB (0.41) | CASP3RAB9AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |