Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680897 | 0.88 | ALDH1A1 (0.43) | SMN1; SMN2L3MBTL1KMT2AMEN1HTT | |
| SCHEMBL9682106 | 0.88 | ALDH1A1 (0.42) | SMN1; SMN2L3MBTL1KMT2AMEN1HTT | |
| SCHEMBL9681489 | 0.85 | ALDH1A1 (0.41) | SMN1; SMN2L3MBTL1KMT2AMEN1HTT | |
| SCHEMBL9681507 | 0.85 | CASP1 (0.42) | HTTKDM4EALDH1A1GAAGLA | |
| SCHEMBL9680406 | 0.84 | POLB (0.45) | SMN1; SMN2L3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL9681433 | 0.82 | CFTR (0.42) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL9682059 | 0.81 | MAPT (0.45) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9682898 | 0.74 | RARA (0.32) | KDM4EMAPTNPSR1 | |
| SCHEMBL9682129 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL9680361 | 0.72 | KDM4E (0.36) | KMT2AMEN1KDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |