Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682059 | 0.91 | MAPT (0.45) | BRD4MAPTALDH1A1KDM4ETP53 | |
| SCHEMBL9680406 | 0.89 | POLB (0.45) | BRD4BRD2BRD3BRDTPOLB | |
| SCHEMBL9680402 | 0.89 | RARA (0.39) | BRD4POLBMAPTALDH1A1KDM4E | |
| SCHEMBL9680331 | 0.83 | RARA (0.40) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9680897 | 0.83 | ALDH1A1 (0.43) | BRD4BRD2BRD3BRDTPOLB | |
| SCHEMBL9680903 | 0.82 | SMN1; SMN2 (0.41) | BRD4BRD2BRD3BRDTMAPT | |
| SCHEMBL9682106 | 0.82 | ALDH1A1 (0.42) | BRD4BRD2BRD3BRDTPOLB | |
| SCHEMBL9681507 | 0.80 | CASP1 (0.42) | CFTRMAPTALDH1A1KDM4EGLA | |
| SCHEMBL9681489 | 0.80 | ALDH1A1 (0.41) | BRD4BRD2BRD3BRDTPOLB | |
| SCHEMBL12365911 | 0.78 | RARA (0.43) | POLBMAPTALDH1A1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |