Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681433 | 0.89 | CFTR (0.42) | POLBRXFP1BRD4KDM4EALDH1A1 | |
| SCHEMBL9682059 | 0.87 | MAPT (0.45) | RXFP1BRD4KDM4EALDH1A1GLA | |
| SCHEMBL9680897 | 0.85 | ALDH1A1 (0.43) | POLBBRD4KDM4EALDH1A1GLA | |
| SCHEMBL9680903 | 0.84 | SMN1; SMN2 (0.41) | BRD4KDM4EALDH1A1GLAGAA | |
| SCHEMBL9682106 | 0.84 | ALDH1A1 (0.42) | POLBBRD4KDM4EALDH1A1GLA | |
| SCHEMBL9681507 | 0.82 | CASP1 (0.42) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL9681489 | 0.82 | ALDH1A1 (0.41) | POLBBRD4KDM4EALDH1A1GLA | |
| SCHEMBL9680402 | 0.77 | RARA (0.39) | POLBBRD4KDM4EALDH1A1MAPT | |
| SCHEMBL9193746 | 0.72 | POLB (0.44) | POLBRXFP1BRD4KDM4EALDH1A1 | |
| SCHEMBL9682898 | 0.71 | RARA (0.32) | KDM4EMAPTRARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |