Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681433 | 0.91 | CFTR (0.42) | MAPTLMNAMAPK10MEN1KMT2A | |
| SCHEMBL9680406 | 0.87 | POLB (0.45) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9680897 | 0.82 | ALDH1A1 (0.43) | MAPTLMNARECQLSMN1; SMN2MEN1 | |
| SCHEMBL9682106 | 0.81 | ALDH1A1 (0.42) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9680903 | 0.81 | SMN1; SMN2 (0.41) | MAPTTHRBLMNASMN1; SMN2MEN1 | |
| SCHEMBL9681507 | 0.79 | CASP1 (0.42) | MAPTRECQLALDH1A1KDM4EGLA | |
| SCHEMBL9681489 | 0.79 | ALDH1A1 (0.41) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9680374 | 0.76 | ALDH1A1 (0.42) | MAPTRECQLSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9194983 | 0.74 | MAPT (0.44) | MAPTTHRBLMNAF2RL3RECQL | |
| SCHEMBL9680331 | 0.74 | RARA (0.40) | MAPTLMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |