Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681265 | 0.81 | BCHE (0.46) | HDAC1HDAC6HDAC2HDAC8HDAC10 | |
| SCHEMBL727322 | 0.79 | ALDH1A1 (0.57) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL9681080 | 0.79 | ALDH1A1 (0.57) | HDAC1HDAC6HPGDALDH1A1MAPT | |
| SCHEMBL2402208 | 0.76 | L3MBTL1 (0.47) | HDAC4HPGDALDH1A1MAPTRAB9A | |
| SCHEMBL9681018 | 0.75 | ALDH1A1 (0.50) | HDAC1HDAC6HDAC2HDAC8HDAC10 | |
| SCHEMBL855138 | 0.75 | ALDH1A1 (0.61) | HDAC1HDAC6HPGDALDH1A1MAPT | |
| SCHEMBL10891605 | 0.75 | THRB (0.56) | MAPT | |
| SCHEMBL9681134 | 0.75 | MAPT (0.68) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL11258091 | 0.74 | KDM4E (0.49) | HPGDRAB9ANPC1MEN1KMT2A | |
| SCHEMBL194873 | 0.73 | ALDH1A1 (0.59) | HDAC1HDAC6HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0138754-B1 | PHOTOCURABLE COMPOSITIONS | CIBA-GEIGY AG (CH) | 1988-05-25 | — | — | EP | disclosed |
| EP-0138754-A2 | Photocurable compositions | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |