SCHEMBL9682298

SCHEMBL9682298

CC(CN(C#N)Cc1nccc(OCc2ccccc2)c1OCc1ccccc1)N(C#N)Cc1nccc(OCc2ccccc2)c1OCc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.34
ALDH1A1 P00352 5/20 0.33
SGMS2 Q8NHU3 7/20 0.32
BCHE P06276 1/20 0.32
LMNA P02545 4/20 0.32
CYP1A2 P05177 3/20 0.32
CYP2C9 P11712 3/20 0.32
KDM4E B2RXH2 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
POLB P06746 1/20 0.32
PKM P14618 1/20 0.32
ALOX12 P18054 1/20 0.32
LTA4H P09960 1/20 0.32
MAPK14 Q16539 1/20 0.32
MAPK1 P28482 2/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11507988 0.73 ALDH1A1 (0.59) GRM2ALDH1A1LMNACYP1A2CYP2C9
SCHEMBL9682296 0.72 BCHE (0.38) BCHECYP1A2CYP2C9CYP3A4CYP2D6
SCHEMBL9654512 0.67 LTA4H (0.45) SGMS2LMNAPOLBLTA4HMAPK14
SCHEMBL4898090 0.67 LTA4H (0.45) SGMS2LMNACYP1A2KDM4ECYP2C19
Hydrochloric Acid SCHEMBL9683438 0.66 LTA4H (0.44) ALDH1A1SGMS2LMNAPOLBLTA4H
SCHEMBL9683651 0.65 MEN1 (0.38) ALDH1A1SGMS2LMNAKDM4ELTA4H
SCHEMBL9681836 0.64 LMNA (0.47) ALDH1A1BCHELMNAKDM4EPOLB
SCHEMBL4898749 0.64 L3MBTL1 (0.53) LMNAPOLBLTA4HMAPK14MAPK1
SCHEMBL4891121 0.64 ALDH1A1 (0.55) ALDH1A1SGMS2LMNACYP2C9KDM4E
SCHEMBL9683450 0.63 LMNA (0.49) ALDH1A1BCHELMNAKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013841-A1 COMPLEXING AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1992-08-20 WO disclosed
EP-0498380-A1 Complexing agents BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1992-08-12 EP disclosed