Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 7/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682780 | 1.00 | AKR1B10 (0.48) | AKR1B10AKR1B1MAOBHCAR2MAPK1 | |
| SCHEMBL9682217 | 0.90 | AKR1B10 (0.46) | AKR1B10AKR1B1MAOBHCAR2MAPK1 | |
| SCHEMBL29236452 | 0.87 | TOP2A (0.51) | AKR1B10AKR1B1HCAR2MAPK1ALOX5 | |
| SCHEMBL9683489 | 0.83 | LMNA (0.57) | AKR1B10AKR1B1HCAR2MAPK1LMNA | |
| SCHEMBL9682234 | 0.81 | ALDH1A1 (0.42) | AKR1B10AKR1B1MAPK1LMNAKDM4E | |
| SCHEMBL9682243 | 0.81 | ALDH1A1 (0.42) | AKR1B10AKR1B1MAPK1LMNAKDM4E | |
| SCHEMBL9682795 | 0.79 | KMT2A (0.54) | MAPK1APPKDM4ECYP3A4ALOX15 | |
| SCHEMBL9682211 | 0.79 | KMT2A (0.54) | MAPK1APPKDM4ECYP3A4ALOX15 | |
| SCHEMBL15929684 | 0.77 | AKR1B10 (0.76) | AKR1B10AKR1B1MAOBHCAR2MAPK1 | |
| SCHEMBL18393355 | 0.77 | AKR1B10 (0.76) | AKR1B10AKR1B1MAOBHCAR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089377-A | Acridin-9-yl acrylates | ASAHI DENKA KOGYO K.K. (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4985564-A | Acridine compound and photopolymerizable composition using the same | HITACHI CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |