Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 4/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682217 | 0.84 | AKR1B10 (0.46) | LMNAAKR1B10AKR1B1HCAR2ALDH1A1 | |
| SCHEMBL9682780 | 0.83 | AKR1B10 (0.48) | LMNAAKR1B10AKR1B1HCAR2TTR | |
| SCHEMBL9682777 | 0.83 | AKR1B10 (0.48) | LMNAAKR1B10AKR1B1HCAR2TTR | |
| SCHEMBL29236452 | 0.82 | TOP2A (0.51) | LMNAAKR1B10AKR1B1HCAR2ALDH1A1 | |
| SCHEMBL9682234 | 0.81 | ALDH1A1 (0.42) | LMNAAKR1B10AKR1B1ALDH1A1POLB | |
| SCHEMBL9682243 | 0.81 | ALDH1A1 (0.42) | LMNAAKR1B10AKR1B1ALDH1A1POLB | |
| SCHEMBL9682795 | 0.79 | KMT2A (0.54) | CA12CA7CA9CA14TTR | |
| SCHEMBL9682211 | 0.79 | KMT2A (0.54) | CA12CA7CA9CA14TTR | |
| SCHEMBL13833759 | 0.77 | LMNA (0.93) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL3704563 | 0.76 | KDM4E (0.54) | LMNACA4HCAR2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089377-A | Acridin-9-yl acrylates | ASAHI DENKA KOGYO K.K. (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4985564-A | Acridine compound and photopolymerizable composition using the same | HITACHI CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0360443-A1 | Acridine compound and photopolymerizable composition using the same | Hitachi Chemical Co., Ltd. (JP) | 1990-03-28 | — | — | EP | disclosed |