Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683956 | 0.76 | ALB (0.42) | KMT2AHSD17B10 | |
| SCHEMBL23908712 | 0.72 | ALDH1A1 (0.58) | TSHRALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL10671377 | 0.70 | ALDH1A1 (0.37) | ALDH1A1KMT2AKDM4E | |
| SCHEMBL80183 | 0.66 | ALDH1A1 (0.64) | TSHRALDH1A1KMT2AMEN1AKR1B1 | |
| Bicarbonate SCHEMBL4865957 | 0.66 | CYP2A6 (0.59) | TSHRALDH1A1KMT2AMEN1NPSR1 | |
| Bicarbonate SCHEMBL11009844 | 0.66 | CYP2A6 (0.59) | TSHRALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL31589562 | 0.66 | HSD17B10 (0.58) | TSHRALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL9256434 | 0.66 | CYP2A6 (0.36) | TSHRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL503745 | 0.66 | MAOA (0.50) | TSHRALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL30895284 | 0.66 | MAOA (0.50) | TSHRALDH1A1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134147-A | Antipsychotic agents | ADIR ET COMPAGNIE (FR) | 1992-07-28 | — | — | US | disclosed |
| US-5100902-A | Dopamine and Serotonin Antagonists, Antipsychotic Agents | ADIR ET COMPAGNIE (FR) | 1992-03-31 | — | — | US | disclosed |