Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682799 | 0.76 | TSHR (0.44) | HSD17B10KMT2A | |
| SCHEMBL1927711 | 0.68 | FOLH1 (0.53) | ALBCES2CES1TTRRAB9A | |
| SCHEMBL10671377 | 0.66 | ALDH1A1 (0.37) | CA1CA2CA7CA9HTT | |
| SCHEMBL260553 | 0.66 | CES2 (0.67) | ALBCES2CES1TTRNPC1 | |
| SCHEMBL31589562 | 0.66 | HSD17B10 (0.58) | CA9HPGDHSD17B10KMT2A | |
| SCHEMBL503745 | 0.66 | MAOA (0.50) | TTRCA1CA2CA9KMT2A | |
| SCHEMBL30895284 | 0.66 | MAOA (0.50) | TTRCA1CA2CA9KMT2A | |
| SCHEMBL16875857 | 0.65 | GPR35 (0.41) | CES2CES1TTRACMSDKMT2A | |
| Hydrochloric Acid SCHEMBL7968059 | 0.64 | CES2 (0.64) | ALBCES2CES1TTRNPC1 | |
| SCHEMBL3117223 | 0.64 | CES2 (0.64) | ALBCES2CES1TTRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134147-A | Antipsychotic agents | ADIR ET COMPAGNIE (FR) | 1992-07-28 | — | — | US | disclosed |
| US-5100902-A | Dopamine and Serotonin Antagonists, Antipsychotic Agents | ADIR ET COMPAGNIE (FR) | 1992-03-31 | — | — | US | disclosed |