Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846250 | 0.74 | PIK3CD (0.43) | ALDH1A1KDM4EMAPT | |
| SCHEMBL9680689 | 0.74 | PIK3CD (0.43) | ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL9432107 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL9076045 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL25372132 | 0.68 | RARA (0.34) | — | |
| SCHEMBL28874496 | 0.67 | MAPK1 (0.44) | ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL24029488 | 0.67 | GABRP (0.36) | ALDH1A1KDM4EMAPT | |
| SCHEMBL25113501 | 0.66 | FBP1 (0.36) | — | |
| SCHEMBL14327833 | 0.65 | MTNR1A (0.31) | — | |
| SCHEMBL25370494 | 0.65 | NOTUM (0.37) | ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |