Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684850 | 0.76 | ATP4A (0.52) | KDM4EALDH1A1 | |
| Iodide SCHEMBL2830855 | 0.72 | KDM4E (0.52) | KDM4EALDH1A1 | |
| SCHEMBL9685709 | 0.69 | KDM4E (0.46) | KDM4EALDH1A1 | |
| SCHEMBL9685162 | 0.65 | KDM4E (0.86) | KDM4EALDH1A1 | |
| SCHEMBL27730947 | 0.65 | ROCK1 (0.49) | ALDH1A1 | |
| SCHEMBL20490797 | 0.63 | TUBB4A (0.65) | KDM4EALDH1A1 | |
| SCHEMBL8484042 | 0.63 | KDM4E (0.52) | KDM4EALDH1A1 | |
| SCHEMBL13312024 | 0.61 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL9687149 | 0.60 | KDM4E (0.63) | KDM4EALDH1A1 | |
| SCHEMBL9685739 | 0.60 | KDM4E (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307078-B1 | QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1992-08-26 | — | — | EP | disclosed |
| US-5051508-A | Antisecretory agents and enzyme inhibitors as antiulcer agents | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1991-09-24 | — | — | US | disclosed |
| EP-0307078-A1 | Quinoline derivatives, process for their preparation and pharmaceutical compositions containing them | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1989-03-15 | — | — | EP | disclosed |