Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | CASP1 | P29466 | 4/20 | 0.42 |
| ▸ | CASP7 | P55210 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686157 | 0.78 | NPSR1 (0.55) | PRMT1ALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL11583159 | 0.77 | LMNA (0.59) | ALDH1A1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL9684556 | 0.76 | LMNA (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL1618023 | 0.76 | PRMT1 (0.61) | PRMT1ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL9684629 | 0.75 | PRMT1 (0.51) | PRMT1ALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL9298122 | 0.75 | PRMT1 (0.51) | PRMT1ALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL9685436 | 0.75 | PRMT1 (0.51) | PRMT1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9685366 | 0.75 | PTPN11 (0.59) | PRMT1ALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL11870333 | 0.74 | TRPA1 (0.46) | PRMT1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8812552 | 0.74 | ALOX15 (0.51) | PRMT1ALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61060687-A | — | — | None | — | — | JP | disclosed |
| EP-0188094-B1 | QUINAZOLINE DERIVATIVES AND ANTIHYPERTENSIVE PREPARATIONS CONTAINING SAME AS EFFECTIVE COMPONENTS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4734418-A | Quinazoline compounds and antihypertensives | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0188094-A2 | Quinazoline derivatives and antihypertensive preparations containing same as effective components | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |
| JP-S6160687-A | PYRIDOPYRIMIDINE DERIVATIVE AND ITS PRODUCTION | MITSUI PETROCHEM IND LTD | 1986-03-28 | — | — | JP | disclosed |