Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.50 |
| ▸ | TUBB | P07437 | 7/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685728 | 0.82 | PDE3B (0.69) | SMN1; SMN2PDE3BPDE3AHTR1AHTR2C | |
| SCHEMBL9686038 | 0.77 | ALDH1A1 (0.51) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL9686113 | 0.76 | PGR (0.50) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL9205683 | 0.75 | HTR1A (0.53) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL9484835 | 0.75 | SMN1; SMN2 (0.67) | SMN1; SMN2PDE3BPDE3ATUBB4ATUBB | |
| SCHEMBL9685648 | 0.74 | CMA1 (0.56) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL9204486 | 0.73 | MAPT (0.59) | SMN1; SMN2PDE3BPDE3AHTR1AHTR2C | |
| SCHEMBL8910416 | 0.72 | PTGS2 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11206860 | 0.71 | PDE3B (0.61) | SMN1; SMN2PDE3BPDE3AHTR1AHTR2C | |
| SCHEMBL9685633 | 0.70 | KIF11 (0.51) | PDE3BPDE3AHTR1AHTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |