Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205683 | 0.85 | HTR1A (0.53) | PDE3BPDE3AMAPTHTR1AHTR2C | |
| SCHEMBL435577 | 0.84 | PDE3B (0.59) | ALDH1A1PKMPDE3BPDE3AMAPT | |
| SCHEMBL9685648 | 0.84 | CMA1 (0.56) | ALDH1A1PDE3BPDE3AMAPTHTR1A | |
| SCHEMBL9685728 | 0.83 | PDE3B (0.69) | ALDH1A1PDE3BPDE3AMAPTHTR1A | |
| SCHEMBL9685633 | 0.80 | KIF11 (0.51) | PDE3BPDE3AMAPTHTR1AHTR2C | |
| SCHEMBL9204486 | 0.80 | MAPT (0.59) | ALDH1A1PKMPDE3BPDE3AMAPT | |
| SCHEMBL9686113 | 0.79 | PGR (0.50) | ALDH1A1PDE3BPDE3AMAPTHTR1A | |
| SCHEMBL9484426 | 0.78 | PDE3B (0.68) | ALDH1A1PKMPDE3BPDE3AMAPT | |
| SCHEMBL9685980 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1PDE3BPDE3AMAPTHTR1A | |
| SCHEMBL9684901 | 0.77 | PDE3B (0.51) | PDE3BPDE3AMAPTHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |