Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684465 | 0.83 | MAPT (0.51) | MAPTALDH1A1LMNAHTTFGFR1 | |
| SCHEMBL9683960 | 0.83 | GRK6 (0.49) | MAPTALDH1A1LMNAHTTFGFR1 | |
| SCHEMBL9685946 | 0.81 | KEAP1 (0.51) | MAPTALDH1A1LMNAHTTTTR | |
| SCHEMBL18463232 | 0.77 | MAPT (0.69) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9423239 | 0.74 | MAPT (0.38) | MAPTALDH1A1CYP3A4LMNAHTT | |
| SCHEMBL9684529 | 0.71 | ALDH1A1 (0.40) | MAPTALDH1A1CYP1A2CYP3A4LMNA | |
| SCHEMBL9685886 | 0.71 | CDC25B (0.42) | MAPTALDH1A1CYP1A2CYP3A4LMNA | |
| SCHEMBL9684787 | 0.71 | SOAT1 (0.39) | MAPTALDH1A1CYP1A2CYP3A4LMNA | |
| SCHEMBL9684783 | 0.71 | MAPT (0.37) | MAPTALDH1A1CYP1A2CYP3A4LMNA | |
| SCHEMBL10823593 | 0.69 | MAPT (0.68) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |