Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328275 | 0.97 | CTSL (0.35) | CTSLCTSBCTSKDRD2HTR2A | |
| SCHEMBL7321608 | 0.95 | NAAA (0.35) | CTSLCTSBCTSKNAAA | |
| SCHEMBL7323296 | 0.93 | CTSL (0.37) | CTSLCTSBCTSKDRD2HTR2A | |
| SCHEMBL7303445 | 0.91 | CTSL (0.41) | CTSLCTSBCTSKNAAA | |
| SCHEMBL9685940 | 0.88 | CTSL (0.41) | CTSLCTSBCTSKNAAA | |
| SCHEMBL7294313 | 0.86 | NAAA (0.40) | CTSLCTSBCTSKNAAA | |
| SCHEMBL9686027 | 0.85 | ADRB1 (0.40) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL7303225 | 0.85 | ADRB1 (0.41) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL6347240 | 0.84 | CTSL (0.43) | CTSLCTSBCTSKNAAA | |
| SCHEMBL9686839 | 0.84 | DRD2 (0.47) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135932-A | 2-HYDROXYPROPYLAMINO-ALKYL-BENZIMIDAZOLY-5-YL DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEART DISEASE | DR. KARL THOMAE GMBH (DE) | 1992-08-04 | — | — | US | disclosed |