Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685940 | 0.92 | CTSL (0.41) | CTSLCTSBCTSKNAAA | |
| SCHEMBL7303445 | 0.92 | CTSL (0.41) | CTSLCTSBCTSKNAAA | |
| SCHEMBL7323296 | 0.91 | CTSL (0.37) | CTSLCTSBCTSKNAAA | |
| SCHEMBL7294313 | 0.91 | NAAA (0.40) | CTSLCTSBCTSKNAAA | |
| SCHEMBL7328275 | 0.84 | CTSL (0.35) | CTSLCTSBCTSKNAAA | |
| SCHEMBL9687339 | 0.84 | CTSL (0.35) | CTSLCTSBCTSKNAAA | |
| SCHEMBL7321608 | 0.83 | NAAA (0.35) | CTSLCTSBCTSKNAAA | |
| SCHEMBL4621588 | 0.81 | ADRB1 (0.43) | — | |
| SCHEMBL7297442 | 0.79 | SIGMAR1 (0.51) | — | |
| SCHEMBL1928095 | 0.79 | TSHR (0.58) | CTSLCTSBCTSKNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731954-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RES INC (US) | 2023-08-22 | — | — | US | disclosed |
| US-20210238161-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2021-08-05 | — | — | US | disclosed |
| US-11001568-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20200157077-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2020-05-21 | — | — | US | disclosed |
| US-10604525-B2 | Pyrazolopyrimidine derivatives | BAYAL ANIMAL HEALTH GMBH (DE) | 2020-03-31 | — | — | US | disclosed |
| US-10597379-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2020-03-24 | — | — | US | disclosed |
| US-20190071447-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-03-07 | — | — | US | disclosed |
| US-20180319769-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-11-08 | — | — | US | disclosed |
| US-20050101783-A1 | N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide | KUREHA CORPORATION (JP) | 2005-05-12 | — | — | US | disclosed |
| US-5135932-A | 2-HYDROXYPROPYLAMINO-ALKYL-BENZIMIDAZOLY-5-YL DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEART DISEASE | DR. KARL THOMAE GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0400519-A1 | 2-Hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them | Dr. Karl Thomae GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101783-A1 | N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide | HBZ, ACMSD, HDHD5 | CTSL 3309/4885CTSB 4059/4885CTSK 3337/4885 |
| US-10604525-B2 | Pyrazolopyrimidine derivatives | P2RX5, RECQL, P2RX1 | CTSL 1867/4885CTSB 2792/4885CTSK 2148/4885 |
| US-11001568-B2 | Histone demethylase inhibitors | KDM1B, KDM1A, BMI1 | CTSL 4588/4885CTSB 3722/4885CTSK 3850/4885 |
| US-10597379-B2 | Histone demethylase inhibitors | KDM1B, KDM1A, BMI1 | CTSL 4588/4885CTSB 3722/4885CTSK 3850/4885 |
| US-11731954-B2 | Histone demethylase inhibitors | KDM1B, KDM1A, BMI1 | CTSL 4588/4885CTSB 3722/4885CTSK 3850/4885 |
| US-20190071447-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | P2RX5, RECQL, P2RX1 | CTSL 1867/4885CTSB 2792/4885CTSK 2148/4885 |
| US-20180319769-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, BMI1 | CTSL 4588/4885CTSB 3722/4885CTSK 3850/4885 |
| US-20200157077-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, BMI1 | CTSL 4588/4885CTSB 3722/4885CTSK 3850/4885 |
| US-20210238161-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, BMI1 | CTSL 4588/4885CTSB 3722/4885CTSK 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.