Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 4/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.45 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686654 | 0.82 | PPIA (0.63) | PPIAGAASGMS2 | |
| SCHEMBL7599768 | 0.82 | EPHX2 (0.58) | KCNJ5KCNJ3GAATDP1 | |
| SCHEMBL11392733 | 0.79 | SCD (0.54) | PPIASCDGAA | |
| SCHEMBL11248869 | 0.78 | TDP1 (0.64) | PPIAKCNJ5KCNJ3TDP1 | |
| SCHEMBL9687933 | 0.78 | EPHX2 (0.53) | PPIAKCNJ5KCNJ3GAATDP1 | |
| SCHEMBL3806426 | 0.76 | SGMS2 (0.53) | PPIASCDGAASGMS2 | |
| SCHEMBL11244391 | 0.76 | PPARA (0.49) | PPIAMRGPRX4 | |
| SCHEMBL11236840 | 0.76 | LRRK2 (0.50) | PPIAMRGPRX4LRRK2GAATDP1 | |
| SCHEMBL11242537 | 0.75 | ACP1 (0.54) | PPIAMRGPRX4LRRK2 | |
| SCHEMBL4255007 | 0.75 | PPIA (0.64) | PPIAMRGPRX4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166180-A | Administering diphenyl substituted (thio)carbonyl(thio)urea derivatives | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-11-24 | — | — | US | disclosed |
| EP-0324521-A2 | Method of treating haematologic diseases and pharmaceutical compositions to be used therefor | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-07-19 | — | — | EP | disclosed |