Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689043 | 0.74 | HPGD (0.39) | KMT2AMEN1HTTSMN1; SMN2NPC1 | |
| SCHEMBL9687941 | 0.73 | EZH2 (0.40) | KMT2AMEN1HTTSMN1; SMN2NPC1 | |
| SCHEMBL9688130 | 0.69 | LMNA (0.43) | KMT2AMEN1HTTSMN1; SMN2NPC1 | |
| SCHEMBL9687391 | 0.68 | HPGD (0.39) | KMT2AMEN1HTTSMN1; SMN2NPC1 | |
| SCHEMBL9687454 | 0.67 | MEN1 (0.39) | KMT2AMEN1HTTKDM4EALDH1A1 | |
| SCHEMBL8765637 | 0.65 | HPGD (0.61) | KMT2AMEN1HTTSMN1; SMN2NPC1 | |
| SCHEMBL34468877 | 0.64 | HPGD (0.61) | KMT2AMEN1HTTNPC1HDAC1 | |
| SCHEMBL8062343 | 0.64 | TAAR1 (0.58) | KMT2AALDH1A1GAAMAPT | |
| SCHEMBL30136331 | 0.64 | TAAR1 (0.58) | KMT2AALDH1A1GAAMAPT | |
| SCHEMBL6848785 | 0.64 | HTT (0.83) | KMT2AMEN1HTTNPC1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |