Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687409 | 0.80 | LMNA (0.43) | HTTTSHRMAPTMEN1KMT2A | |
| SCHEMBL9687941 | 0.78 | EZH2 (0.40) | HPGDHTTSMN1; SMN2NPC1MEN1 | |
| SCHEMBL9687454 | 0.77 | MEN1 (0.39) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9686935 | 0.73 | CNR1 (0.47) | ALDH1A1MAPTTP53POLBROCK2 | |
| SCHEMBL23159263 | 0.65 | KDM4E (0.46) | HPGDNPC1ALDH1A1TSHRNPSR1 | |
| SCHEMBL18971053 | 0.64 | TAS1R3 (0.57) | HPGDTAS1R3TAS1R1HTTALDH1A1 | |
| SCHEMBL9164491 | 0.63 | ALDH1A1 (0.34) | HTTSMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL9687418 | 0.62 | POLB (0.34) | SMN1; SMN2MAPTPOLBMEN1KMT2A | |
| SCHEMBL9160957 | 0.59 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL13990807 | 0.59 | KDM4E (0.56) | HPGDNPC1ALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |