Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.32 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7193352 | 0.99 | POLB (0.34) | POLBCYP3A4ALOX15TEAD1TEAD4 | |
| SCHEMBL461683 | 0.92 | CYP3A4 (0.37) | POLBCYP3A4ALOX15HTR2CHTR2A | |
| SCHEMBL8926874 | 0.88 | POLB (0.34) | POLBCYP3A4ALOX15TEAD1TEAD4 | |
| SCHEMBL11080708 | 0.81 | CYP3A4 (0.37) | POLBCYP3A4ALOX15TEAD1TEAD4 | |
| Sulfuric Acid SCHEMBL1424848 | 0.76 | LTB4R (0.38) | CYP3A4ALOX15MAPTELANE | |
| SCHEMBL11667886 | 0.76 | CYP3A4 (0.33) | POLBCYP3A4ALOX15MAPT | |
| SCHEMBL9606474 | 0.73 | CYP3A4 (0.31) | CYP3A4ALOX15MAPT | |
| Acrylic Acid SCHEMBL1261322 | 0.70 | THRB (0.43) | — | |
| SCHEMBL4634142 | 0.70 | GABRA1 (0.46) | POLBCYP3A4MAPT | |
| SCHEMBL11665412 | 0.68 | CYP3A4 (0.39) | POLBCYP3A4ALOX15PTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4696760-A | Method for production of aqueous dispersion of N-substituted N',N'-alkylene urea | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1987-09-29 | — | — | US | claimed |
| US-5143546-A | Inks with adhesion which varies with voltage | CANON KABUSHIKI KAISHA (JP) | 1992-09-01 | — | — | US | disclosed |
| US-5017223-A | Liquid Dispersion Of An Electrolyte Capable Of Changing Its Adhesiveness In Response To Voltage Application | CANON KABUSHIKI KAISHA (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0352796-A2 | Recording material | CANON KABUSHIKI KAISHA (JP) | 1990-01-31 | — | — | EP | disclosed |
| US-4696760-A | Method for production of aqueous dispersion of N-substituted N',N'-alkylene urea | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1987-09-29 | — | — | US | disclosed |
| US-4578314-A | ABRASIVE PARTICLES IN DISPERSION | TDK CORPORATION (JP) | 1986-03-25 | — | — | US | disclosed |