Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690486 | 0.87 | FABP4 (0.47) | FABP4HTR6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9690796 | 0.84 | FABP4 (0.50) | FABP4HTR6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9690953 | 0.80 | GABRP (0.52) | ALDH1A1HPGDHSD17B10KDM4EGLA | |
| SCHEMBL9688920 | 0.75 | FABP4 (0.52) | FABP4HTR6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9382989 | 0.74 | HTR6 (0.44) | FABP4HTR6ALDH1A1KDM4EACHE | |
| SCHEMBL9689722 | 0.73 | FABP4 (0.47) | FABP4HTR6ALDH1A1KDM4ELMNA | |
| SCHEMBL9689821 | 0.73 | GABRP (0.50) | ALDH1A1HPGDHSD17B10KDM4EGLA | |
| SCHEMBL9688937 | 0.72 | GABRP (0.50) | ALDH1A1HPGDHSD17B10KDM4EGLA | |
| SCHEMBL9383301 | 0.72 | CYP11B2 (0.46) | FABP4HTR6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9689811 | 0.71 | GABRP (0.46) | ALDH1A1HPGDHSD17B10KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249301-B1 | Pyrido[2,3-b]indoles | BEECHAM GROUP PLC (GB) | 1992-05-27 | — | — | EP | claimed |