Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 4/20 | 0.41 |
| ▸ | CASP7 | P55210 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689810 | 0.87 | FABP4 (0.43) | FABP4KDM4EALDH1A1GLAGAA | |
| SCHEMBL9688920 | 0.86 | FABP4 (0.52) | FABP4KDM4EALDH1A1GLAGAA | |
| SCHEMBL9690796 | 0.77 | FABP4 (0.50) | FABP4KDM4EALDH1A1GLAGAA | |
| SCHEMBL9690953 | 0.71 | GABRP (0.52) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL9382989 | 0.71 | HTR6 (0.44) | FABP4KDM4EALDH1A1HTR6CYP3A4 | |
| SCHEMBL9382045 | 0.71 | ALDH1A1 (0.46) | FABP4KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9689722 | 0.70 | FABP4 (0.47) | FABP4KDM4EALDH1A1HTR6SMN1; SMN2 | |
| SCHEMBL9383301 | 0.69 | CYP11B2 (0.46) | FABP4KDM4EALDH1A1GLAGAA | |
| SCHEMBL17406863 | 0.66 | FABP4 (0.47) | FABP4KDM4EALDH1A1HTR6SMN1; SMN2 | |
| SCHEMBL9688937 | 0.65 | GABRP (0.50) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249301-B1 | Pyrido[2,3-b]indoles | BEECHAM GROUP PLC (GB) | 1992-05-27 | — | — | EP | claimed |